Drug Delivery with Targeted Nanoparticles: In Vitro and In Vivo Evaluation Methods : In Vitro and In Vivo Evaluation Methods | 1st edition

by Yılmaz Capan and Adem Sahin

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Publisher	Taylor & Francis Ltd
Language	English
Book type	Hardcover
Utgiven	2021-06-30
Edition	1
Pages	850
ISBN	9789814877756
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Description

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared to conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires many evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

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