At New York's JFK Airport an arriving Boeing 777 taxing along a runway suddenly stops dead. All the shades have been drawn, all communication channels have mysteriously gone quiet. Dr. Eph Goodweather, head of a CDC rapid-response team investigating biological threats, boards the darkened plane . . . and what he finds makes his blood run cold.

A terrifying contagion has come to the unsuspecting city, an unstoppable plague that will spread like an all-consuming wildfire—lethal, merciless, hungry . . . vampiric.

And in a pawnshop in Spanish Harlem an aged Holocaust survivor knows that the war he has been dreading his entire life is finally here . . .